A LABEL FREE COLORIMETRIC ASSAY FOR THE DETECTION OF ACTIVE BOTULINUM NEUROTOXIN TYPE A BY SNAP-25 CONJUGATED COLLOIDAL GOLD

A Label Free Colorimetric Assay for the Detection of Active Botulinum Neurotoxin Type A by SNAP-25 Conjugated Colloidal Gold

Botulinum neurotoxins are one of the most potent toxins known to man.Current quadruple topical ointment for dogs methods of detection involve the quantification of the toxin but do not take into account the percentage of the toxin that is active.At present the assay used for monitoring the activity of the toxin is the mouse bioassay, which is lengt

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Reduced mitochondrial pyruvate copyright expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin

Introduction and objectivesMitochondrial pyruvate copyright (MPC) mediates the entry of pyruvate into mitochondria, determining whether pyruvate is incorporated into the Krebs cycle or metabolized in the cytosol.In heart failure (HF), a large amount of pyruvate is metabolized to lactate in the cytosol rather than being oxidized inside nyx 22 brush

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DECENTRALIZED PLANNING IN AN INDIAN STATE: AN EXPLORATORY EXERCISE

In India, the idea of decentralized planning gained momentum after the country became independent in 1947 but its rudimentary practice was not completely unknown before 1947.In post-independent India a number of government committees and commissions had recommended for introduction of decentralized planning at different points of time.The most rema

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